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APRIL 7

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Faculty & Student Biochemistry & Molecular Biology Presentations

* Indicate Undergraduate Co-Authors; Speakers are Listed First

Nathan K. Hepler* and Robert E. Carey “Selaginella moellendorffii has a reduced and highly conserved expansin superfamily with genes more closely related to angiosperms than bryophytes.” Presented at the 15th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, Oct 20, 2012. Presentation was judged as a second place winner in biochemistry division.

 

Kimberly L. Holt* and Walter A. Patton “Synthesis and characterization of peptide-capped ZnS nanoparticles.” Presented at the 14th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, Oct 22, 2011. Presentation was judged as a second place winner in biochemistry division.

 

Nathan K. Hepler*, Sarah A. Beatty* and Robert E. Carey, “Expansins in algal and basal land plant lineages,” Presented at the 14th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, Oct 22, 2011. 

 

Libby Cieniewicz*, Patricia Cunfer and Kristen L. Boeshore “Comparison of the effects of nerve growth factor and spermidine in naive and primed PC-12 cells.” Presented at the 14th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, Oct 22, 2011. 

 

Halley R. Washburn*, Colleen L. Delaney and Walter A. Patton “Approaches to the MALDI-TOF mass spectral analysis of a membrane-bound protein.” Presented at the 14th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, Oct 22, 2011. 

 

Katalyn R. Funk*, Lindsey N. Irvin* and Walter A. Patton “Investigations into the stability of the ATPP domain of E coli GMPS.” Presented at the 14th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, Oct 22, 2011. 

 

Kimberly L. Holt* and Walter A. Patton “Synthesis and characterization of peptide-capped ZnS nanoparticles.” Presented at the 46th Midwest, 39th Great Lakes, Joint Regional ACS Meeting, Saint Louis, MO, Oct 20, 2011.

 

Courtney M Lappas, Phillip D. Domeier* and Veronica. J. Chehata*  "Adenosine A2A receptor activation inhibits T cell activity in a murine model of chronic granulomatous disease."  Presented at the 97th Annual Meeting of the American Association of Immunologists, Baltimore, MD, May 7-11, 2010.

 

Michael P. Schmidt*, Veronica J. Chehata*, Phillip D. Domeier*, Courtney M. Lappas and Anderson L. Marsh  "Use of biocompatible zinc sulfide nanocrystals in phototherapeutic applications."  Presented at the 239th American Chemical Society Meeting, San Francisco, CA, March 21-25, 2010

 

Richard Carr*, Gary Lam*, Greg Wier* and Walter Patton "A Dual Approach to Assessing Domain Interaction in a Dimeric Bi-Functional Protein."  Presented at the 12th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, Maryland, October 2009. Judged second place in biochemistry division.

 

Charles R.Schmidt*, Brandon W. Parks* and Walter A. Patton  "Ruthenium Bipyridine Compounds as SDS-PAGE- and MALDI-Compatible Protein Labels." 11th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 11, 2008. Judged second place in biochemistry division.

 

Greg Wier*, Gary Lam* and Walter A. Patton "Investigating Domain Interactions in E. coli GMP Synthetase through Use of Peptide Phage Display." 11th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 11, 2008. 

 

Eric Wier* and Walter A. Patton "Enhancing the Analysis of Oligonucleotides by MALDI-TOF MS." 11th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 11, 2008. 

 

Richard Carr* and Walter A. Patton  "Functional Domain Interactions in E. coli GMP Synthetase," 11th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 11, 2008. 

 

Patricia Cunfer*, Khevna Shukla* and Kristen Boeshore  "Modeling Neurite regeneration in PC12 cells" 11th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 11, 2008. Judged second place in biochemistry division .

 

Brandon W. Parks*, Marc A. Harris, and Walter A. Patton "Cation-exchange chromatography as a purification step in the preparaton of Ruthenium (II) tris-bipyridine complexes," 72nd Annual Intercollegiate Student Chemists Convention, Elizabethtown College, April 19, 2008.

 

Charles R. Schmidt*, Marc A. Harris and Walter A. Patton  "Ruthenium bipyridine compounds as SDS-PAGE-and MALDI-compatible protein labels," 72nd Annual Intercollegiate Student Chemists Convention, Elizabethtown College, April 19, 2008.

 

Ryan Lucas*, Elizabeth Potts* and Kristen Boeshore "Neurite regeneration in PC12 cells," 22nd National Conference on Undergraduate Research, Salisbury University, Salisbury, MD April 10, 2008.

 

Charles R. Schmidt*, Marc A. Harris and Walter A. Patton  "Ruthenium bipyridine compounds as SDS-PAGE- and MALDI-compatible protein labels," 10th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 15, 2007.  Judged first place in chemistry division.

 

Gary Lam* and Walter A. Patton  "The use of a peptide phage display library to probe domain interactions in E. coli GMP synthetase," 10th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 15, 2007.  Judged second place in biochemistry division.

 

Gary Lam* and Walter A. Patton "Structure-function relationships in a potential chemotherapeutic target," Innoventure, Hershey, PA, Poster #146, May 4, 2007.

 

Walter A. Patton, Marc Harris and Paige E Callan*  "The application of ruthenium tris-bipyridine compounds as labels for peptide chains," National Meeting of the American Society for Biochemistry and Molecular Biology, Washington, DC, Poster #796.7, April 28 - May 2, 2007.

 

Gary Lam* and Walter A. Patton  "The effects of removing the GAT domain from E. coli GMP synthetase," National Meeting of the American Society for Biochemistry and Molecular Biology, Washington, DC, Poster #511.13, April 28 - May 2, 2007.

 

Paige E Callan*, Walter A. Patton and Marc Harris  "Application of ruthenium and osmium tris-bipyridine frameworks as mass markers in MALDI-TOF experiments involving covalently labeled peptide chains," 9th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, Baltimore, MD, October 14, 2006.

 

Paige E Callan*, Walter A. Patton and Marc Harris  "Application of ruthenium and osmium tris-bipyridine frameworks as mass markers in MALDI-TOF experiments involving covalently labeled peptide chains," Abstracts of Papers, 232nd ACS National Meeting, San Francisco, CA, United States, Sept. 10-14, 2006. 

 

AuBrei Weigand* and Owen A. Moe  "Effect of ligands on the conformative response in E. coli GMP synthetase," Abstracts of Papers, 232nd ACS National Meeting, San Francisco, CA, Sept. 10-14, 2006.

 

AuBrei Weigand* and Owen A. Moe "Interdomain Communication in E. coli GMP Synthetase," 70th Annual Intercollegiate Student Chemists Convention, Ursinus College, Collegeville, PA, April 22, 2006.

 

Jessica L. Abbott*, Danielle T. Loughlin* and Walter A Patton  "The effects of removing the ammonia-generating GAT domain from E. coli GMP synthetase," Merck Scholar’s Poster Presentations, American Association for the Advancement of Science National Meeting, St. Louis, MO, February 16, 2006.

 

AuBrei Weigand*, Angela Petiak*, and Owen A. Moe "Interdomain Communication in E. coli GMP Synthetase," 8th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland-Baltimore County, Baltimore, MD, October 15, 2005.

 

Derek M. Hinds* and Walter A. Patton “Properties of the individual domains of E. coli GMP synthetase,” 8th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, October 15, 2005.  Judged first place in Biochemistry division.

 

Danielle T. Loughlin*, Derek M. Hinds*, Jordan M. Newell*, Mary E. Olanich* and Walter A. Patton “Properties of the individual domains of E. coli GMP synthetase ,” American Chemical Society National Meeting, Washington, D.C., August 28, 2005. 

 

Melanie A. Weller*, Jessica L. Abbott* J.L., Sidney Pollack and Walter A. Patton “ Functional characteristics of the ATPP domain of E. coli GMP synthetase ,” American Chemical Society National Meeting, Washington, D.C., August 28, 2005.

 

Jordan M. Newell* and Walter A. Patton “Structure-function relationships in a potential chemotherapeutic target,” Innoventure (Hershey, PA) April 15, 2005.

 

Kelly A. Szuler*, Michael L. Maiorino*, Steven E. Kaylor*, Kaylan A. Greenwald*, Katherine Bakowicz*, Yekaterina N. Belousov*, Rayne M. Keeney* and Luke G. Huggins "Do homeotic genes play a role in the segment specfication of the marine polychaete Streblospio benedicti?" 81st Annual Meeting of the PA Academy of Science, Camp Hill, PA, April 9, 2005.

 

Yun K. Kwon*, Amy Gindhart*, and Owen A. Moe, " The Conformative Response in E. coli GMP Synthetase ," National Meeting of the American Society for Biochemistry and Molecular Biology, San Diego, CA, April 3-4, 2005. Judged first place in national undergraduate research competition.

 

Jordan M. Newell*, Danielle T. Loughlin*, Mary E. Olanich* and Walter A. Patton “ Structural organization in E. coli GMP synthetase ,” National Meeting of the American Society for Biochemistry and Molecular Biology, San Diego, CA, April 3-4, 2005.  Judged first place in national undergraduate research competition.

 

Jessica L. Abbott*, Melanie A. Weller*, Mary E. Olanich*, Sidney Pollack and Walter A. Patton “The effects of removing the ammonia-generating GAT domain from E. coli GMP synthetase ,” 7th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, October 16, 2004.  Judged first place in Biochemistry division.

 

Jordan M. Newell*, Danielle T. Loughlin* and Walter A. Patton “Structural organization in E. coli GMP synthetase ,” 7th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, October 16, 2004.  Judged first place in Biochemistry division.

 

Amanda Goulden*, Marc Harris and Walter A. Patton “Fluorescent ruthenium polypyridine tags for detection and localization of proteins,” 7th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, October 16, 2004.

 

Yun K. Kwon* and Owen A. Moe “Using a new glutamine amidotransferase assay to study the conformative response in E. coli GMP synthetase ,” 7th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, October 16, 2004.  Judged second place in Biochemistry division.

 

Walter A. Patton, Jordan Newell*, Danielle T. Loughlin*, Melanie A. Weller*, and Sidney Pollack " Properties of the Individual Domains of E. coli GMP Synthetase ," American Chemical Society National Meeting, Philadelphia, PA, August 25, 2004.

 

Yun K. Kwon* and Owen A. Moe “HPLC Assay for Glutamine Amidotransferase Domains in Complex Enzyme Systems,” Student Awards Symposium, American Chemical Society National Meeting, Philadelphia, PA, August 24, 2004.

 

Amanda Goulden,* Marc A. Harris, and Walter A. Patton “Fluorescent Ruthenium Polypyridine Tags for Detection and Localization of Proteins," American Chemical Society National Meeting, Philadelphia, PA, August 23, 2004.

 

Jordan Newell* and Walter A. Patton " Recombinant Proteins for the Analysis of Domain Interactions in E. coli GMP Synthetase ," American Society for Biochemistry and Molecular Biology National Meeting, Boston, MA, June 12, 2004.

 

Kaylan A. Greenwald*, Kelly A. Szuler*, Christine Puthawala* and Luke G. Huggins “The role of homeotic genes in the development switch between feeding and non-feeding larvae of the marine polychaete Streblospio benedicti?” 80th Annual Meeting of the PA Academy of Science, Pittsburgh, PA, March 27th, 2004.

 

Walter A. Patton, Abby L. Shumaker*, Jessica L. Abbott* and Mary E. Olanich* "Production of Intein-tagged GMP Synthetase Mutant Proteins," 80th Annual Meeting of the PA Academy of Science, Pittsburgh, PA, March 27, 2004.

 

Mariko Furukawa*, Amy Smith*, and Marc A. Harris “Fluorescent Ruthenium Polypyridine Tags for Immunolocalization of Proteins," American Association for the Advancement of Science National Meeting, Seattle, WA, February 12, 2004.

 

Christine Lightcap*, Jordan Newell*, Sid Pollack, and Walter Patton,“ Generation of Recombinant Proteins to Examine the Dimeric Organization of E. coli GMP Synthetase ”, 6th Annual Undergraduate Research Symposium in the Chemical and Biological Sciences, University of Maryland, Baltimore, MD, November 1, 2003.  Judged second place in Biochemistry Division.

 

Christine M. Lightcap*, Jordan M. Newell* , Sidney Pollack, and Walter A. Patton ,“ Domain Organization in the E. coli GMP Synthetase Dimer, ” 226th National Meeting of the American Chemical Society, New York City, NY, September 8, 2003.

 

Chrisandra M. Bright*, Mollie G. Kedney*, Yun K. Kwon*, and Owen A. Moe “ Effect of Urea and Sodium Chloride on the GAT and ATP Pyrophosphatase Domains of E. coli GMP Synthetase ,” 226th National Meeting of the American Chemical Society, New York, NY, September 8, 2003.

 

Abby L. Shumaker*, Mollie G. Kedney*, Mark L. Prinzivalli*, Walter A. Patton, Owen A. Moe “ Effect of Sodium Chloride and Urea on GAT and ATP Pyrophosphatase Domains of E. coli GMP Synthetase ,” Southeastern Regional Meeting of the American Chemical Society, Charleston, SC, November 15, 2002.

 

Mollie G. Kedney*, Abby L. Shumaker*, Mark L. Prinzivalli*, Walter A. Patton, Owen A. Moe “ Ammonia Transfer Between GAT and ATP Pyrophosphatase Domains of E. coli GMP Synthetase ,” Southeastern Regional Meeting of the American Chemical Society, Charleston, SC, November 14, 2002.

 

Mollie G. Kedney*, Abby L. Shumaker*, Mark L. Prinzivalli*, Walter A. Patton, Owen A. Moe “ Effect of Sodium Chloride and Urea on GAT and ATP Pyrophosphatase Domains of E. coli GMP Synthetase ,” Undergraduate Research Symposium, University of Maryland Baltimore, October 9, 2002.

 

Abby L. Shumaker*, Mollie G. Kedney*, Mark L. Prinzivalli*, Walter A. Patton, Owen A. Moe “ Effect of Urea on GAT and ATP Pyrophosphatase Domains of E. coli GMP Synthetase ,” Undergraduate Research Symposium, University of Maryland Baltimore, October 9, 2002.   Judged as top paper in biochemistry division.

 

Craig Menges*, Derek Fisher*, Owen A. Moe, and Walter A. Patton “Elucidation of Active Site Residues in E. coli Guanosine-5´-Phosphate Synthetase,” American Society for Biochemistry and Molecular Biology National Meeting, Orlando, FL, March 31, 2001. Judged one of the top six papers (of 88 total) in national undergraduate research competition.

 

Derek Fisher*, Brian Patson*, Carl T. Wigal, and Owen A. Moe “Use of Molecular Modeling to Elucidate Steric Aspects of the Binding of Quinones to Quinone Reductase,” presented at the American Chemical Society National Meeting, , Washington, DC, November 7, 2000.

 

Brian Patson*, Jared L. Spidel*, Jodi L. Greenfield*, Aleem N. Fazal*, Carl T. Wigal, and Owen A. Moe “Role of Substituents on the Binding and Reactivity of Quinones to Rat-Liver Quinone Reductase,” 13th National Conference on Undergraduate Research, Rochester, NY. April 8, 1999.

 

Jared L. Spidel*, Brian Patson*, Jodi L. Greenfield*, Aleem N. Fazal*, Carl T. Wigal, and Owen A. Moe “Binding and Reactivity of Quinone Substrates of Rat-Liver Quinone Reductase,” presented at the Southeastern Regional Meeting of the American Chemical Society, Research Triangle Park, NC, November 7, 1998.

 

Fei Liu*, An Do*, Jared Spidel*, Jodi Greenfield*, and Owen A. Moe, " Inactivation of E. coli GMP Synthetase by Reactive Analogs of GMP and ATP ," Annual Meeting of the American Society for Biochemistry and Molecular Biology, Washington, DC, May 16, 1998.

 

Jodi L. Greenfield*, An Do*, Fei Liu*, Jared L. Spidel*, and Owen A. Moe, " Affinity Labeling of the Nucleotide Binding Sites of E. Coli GMP Synthetase ," Twelfth National Conference on Undergraduate Research, Salisbury, MD, April 25, 1998.

 

Jared Spidel*, An Do*, Fei Liu*, Jodi Greenfield*, and Owen A. Moe, " Inactivation of E. coli GMP Synthetase by a Reactive Analog of GMP ," Intercollegiate Student Chemist's Conference, Bucknell University, Lewisburg, PA, April 4, 1998.

 

Geoff Gowan, Lance Westerhoff* and Thomas G. Owens, "Computer Simulation of Excited State Dynamics and Nonphotochemical Quenching in Photosystem II," 14th Eastern Regional Photosynthesis Conference, Woods Hole, MA, March, 1997.

 

Lance M. Westerhoff*, Tara L. Fickert*, and Stephen E. Williams, "Modeled Effect of the Spinach CYS172-CYS192 Disulfide Bond on the RUBISCO Active Site," 61st Annual Meeting Northeast Section of American Society of Plant Physiologists, Cornell University, Ithaca, NY, April 19-20, 1997.

 

Owen A. Moe, Jennifer F. Baker-Malcom, Wenyan Wang, Chulhun Kang, Herbert J. Fromm, and Roberta F. Colman, "Arg-143 is at the Active Site of E. coli Adenylosuccinate Synthetase," National Meeting of the American Society of Biochemistry and Molecular Biology, New Orleans, LA, June 3, 1996.

 

Lance M. Westerhoff*, Jeffrey C. Raber*, Stephen E. Williams, "A Phylogeny of Photosynthetic Bacteria and Chloroplast Based on Parsimony Analysis of Type I Ribulose-1, 5-Bisphosphate Carboxylase/Oxygenase (RuBisCo)," 72nd Annual Meeting of the PA Academy of Science, Penn State University, April 12-14, 1996.

 

Lance M. Westerhoff*, Stephen E. Williams, "Matrixor: A New Program for Alignment of Nucleotide Sequences that Code for Protein," 72nd Annual Meeting of the Pennsylvania Academy of Science, Penn State University, April 12-14, 1996.

 

Melissa A. Vargo*, Paul E. Richardson*, Cart T. Wigal, "The Distribution of 5-Hydroxy-1,4 Naphthoquinone (Juglone) in the Juglandaceae with Emphasis on the Genus Carya (Hickory)," 72nd Annual Meeting of the Pennsylvania Academy of Science, Penn State University, April 12-14, 1996.

 

Jeffrey C. Raber*, Lance M. Westerhoff*, Owen A. Moe, "A Model of the Evolution of Type I Ribulose-1,5-Biphosphate Carboxylase/ Oxygenase from the Common Ancestor of the Spinach Chloroplast and Synechococcus," 72nd Annual Meeting of the Pennsylvania Academy of Science, Penn State University, April 12-14, 1996.

 

Paul E. Richardson*, Melissa A. Vargo*, Stephen E. Williams, "A Cladistic Analysis of the Genus Carya (Hickory)," 72nd Annual Meeting of the Pennsylvania Academy of Science, Penn State University, April 12-14, 1996.

 

Amy M. Bonser* and Owen A. Moe, "Gradient HPLC Separation of Platinum-Labeled Adducts of Cytochrome c," Nineteenth Annual Conference of the Federation of Analytical Chemistry and Spectroscopy Societies, Philadelphia, PA, September 23, 1992.

 

Shawnee Lee* and Donald Dahlberg, "FTIR and Chemometric Analysis of Edible Oils," Intercollegiate Student Chemist's Conference, Franklin and Marshall College, PA, April 11, 1992; judged first place in the Analytical Division.

 

Lance Dieter*, Patricia A. Haeusler*, Karla J. Rittle*, Laura Shepler*, and O.A. Moe, Jr., "Determination of the Catalytic Properties of E. coli Polyphosphate Kinase," Intercollegiate Student Chemists' Conference, Bloomsburg University, PA, April 20, 1991.

 

Owen A. Moe, Jr., Christian S. Hamann*, and David P. Myers*, "Amino Acid Analysis by Gas Chromatography/Mass Spectrometry," Symposium on NSF-Catalyzed Innovations in the Undergraduate Laboratory, American Chemical Society National Meeting, Miami Beach, FL, September 12, 1989.

 

David P. Myers*, Christian S. Hamann*, and O. A. Moe, Jr., "Amino Acid Composition Using Gas Chromatography / Mass Spectrometry," Student Awards Symposium, Middle Atlantic Regional Meeting of the American Chemical Society, Cherry Hill, NJ, May 25, 1989.

 

Christian Hamann* and Owen A. Moe, Jr., "Amino Acid Composition Using Gas Chromatography/Mass Spectrometry," Intercollegiate Student Chemist Convention, Juniata College, PA, April 16, 1988. Judged first place in the Biochemistry Division.

 

Joan M. Hevel* and Owen A. Moe, Jr., "Purification of Polyphosphate Kinase for Use in ATP Regeneration," Intercollegiate Student Chemist Convention, Juniata College, PA, April 16, 1988. Judged second place in the Biochemistry Division.

 

Mary Beth Seasholtz* and Owen A. Moe, Jr., "A Spectrophotometric Method for Determining Protein Diffusion Coefficients," Mid-Atlantic Regional Meeting of the American Chemical Society, Stockton State College, Pomona, NJ, May 20, 1987. Awarded first prize as best paper in the Undergraduate Student Research Symposium.

 

Ross Hoffman*, Pamela L. Wyman*, Lynne E. Smith* and Owen A. Moe, Jr., "An Immobilized ATP Regeneration System Based on Polyphosphate Kinase," Mid-Atlantic Regional Meeting of the American Chemical Society, Stockton State College, Pomona, NJ, May 20, 1987. Judged as second place paper in the Undergraduate Student Research Symposium.

 

George Reiner* and Owen A. Moe, Jr., "Spectrophotometric Method for Measuring Protein Diffusion Coefficients," ACS National Meeting, New York City, April 14, 1986.